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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
06/11/2002 |
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Data da última atualização: |
06/11/2002 |
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Autoria: |
ZHANG, J.; MASSMANN, G. A.; MIRABILE, C. P.; FIGUEROA, J. P. |
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Título: |
Nonpregnant sheep uterine type I and type III nitric oxide synthase expression is differentially regulated by estrogen. |
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Ano de publicação: |
1999 |
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Fonte/Imprenta: |
Biology of Reproduction, v. 60, n. 5, p. 1198-1203, 1999. |
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Idioma: |
Inglês |
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Conteúdo: |
The aim of this study was to characterize the effect of estrogen on lhe expression of neuronal and endothelial isoforms of nitric oxide (NO) synthase (NOS) in myometrium, endometrium, and caruncle (nonglandular endometrium) in nonpregnant sheep. Twenty sheep were castrated during synchronized estrus (Days 14-16) and 4 days after surgery treated i.v. through lhe jugular with 100 ug/day of estradiol-17Betha for 5 (n = 6) or 8 (n = 6) days or with vehicle (n = 8). Nitric oxide synthase mRNA was measured by ribonuclease protection assar, and NOS protein mass was measured by Western immunoblotting. Data were analyzed by ANOVA and Tukey's testo The three distinct uterine compartments studied contained lhe mRNA and protein for lhe neuronal (type I NOS) and lhe endothelial (type 111 NOS) isoforms of NOS. However, no inducible NOS was detected. Estrogen exhibited a differential effect on NOS expression in a tissue compartment- and NOS isoform-specific manner. In myometrium and caruncles, but not in endometrium, type I NOS mRNA and protein mass increased significantly (p < 0.05) after 5 or 8 days of estrogen. In contrast, type 111 NOS increased significantly in myometrium only after 8 days, whereas in endometrium and caruncles the increase was significant in the 5-day treatment group (p < 0.05). We conclude that the expression of type I NOS and type 111 NOS in the uterus are differentially regulated by estrogen. This differential regulation suggests that the NO produced within the uterus serves more than one physiological role. In myometrium it mar be a uterorelaxant and regulate glucose utilization, and in endometrium and myometrium it mar regulate blood flow. MenosThe aim of this study was to characterize the effect of estrogen on lhe expression of neuronal and endothelial isoforms of nitric oxide (NO) synthase (NOS) in myometrium, endometrium, and caruncle (nonglandular endometrium) in nonpregnant sheep. Twenty sheep were castrated during synchronized estrus (Days 14-16) and 4 days after surgery treated i.v. through lhe jugular with 100 ug/day of estradiol-17Betha for 5 (n = 6) or 8 (n = 6) days or with vehicle (n = 8). Nitric oxide synthase mRNA was measured by ribonuclease protection assar, and NOS protein mass was measured by Western immunoblotting. Data were analyzed by ANOVA and Tukey's testo The three distinct uterine compartments studied contained lhe mRNA and protein for lhe neuronal (type I NOS) and lhe endothelial (type 111 NOS) isoforms of NOS. However, no inducible NOS was detected. Estrogen exhibited a differential effect on NOS expression in a tissue compartment- and NOS isoform-specific manner. In myometrium and caruncles, but not in endometrium, type I NOS mRNA and protein mass increased significantly (p < 0.05) after 5 or 8 days of estrogen. In contrast, type 111 NOS increased significantly in myometrium only after 8 days, whereas in endometrium and caruncles the increase was significant in the 5-day treatment group (p < 0.05). We conclude that the expression of type I NOS and type 111 NOS in the uterus are differentially regulated by estrogen. This differential regulation suggests that the NO produced within the ute... Mostrar Tudo |
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Thesagro: |
Endocrinologia; Estrógeno; Ovino; Prenhez; Reprodução Animal; Útero. |
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Categoria do assunto: |
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Marc: |
LEADER 02338naa a2200229 a 4500
001 1528831
005 2002-11-06
008 1999 bl uuuu u00u1 u #d
100 1 $aZHANG, J.
245 $aNonpregnant sheep uterine type I and type III nitric oxide synthase expression is differentially regulated by estrogen.
260 $c1999
520 $aThe aim of this study was to characterize the effect of estrogen on lhe expression of neuronal and endothelial isoforms of nitric oxide (NO) synthase (NOS) in myometrium, endometrium, and caruncle (nonglandular endometrium) in nonpregnant sheep. Twenty sheep were castrated during synchronized estrus (Days 14-16) and 4 days after surgery treated i.v. through lhe jugular with 100 ug/day of estradiol-17Betha for 5 (n = 6) or 8 (n = 6) days or with vehicle (n = 8). Nitric oxide synthase mRNA was measured by ribonuclease protection assar, and NOS protein mass was measured by Western immunoblotting. Data were analyzed by ANOVA and Tukey's testo The three distinct uterine compartments studied contained lhe mRNA and protein for lhe neuronal (type I NOS) and lhe endothelial (type 111 NOS) isoforms of NOS. However, no inducible NOS was detected. Estrogen exhibited a differential effect on NOS expression in a tissue compartment- and NOS isoform-specific manner. In myometrium and caruncles, but not in endometrium, type I NOS mRNA and protein mass increased significantly (p < 0.05) after 5 or 8 days of estrogen. In contrast, type 111 NOS increased significantly in myometrium only after 8 days, whereas in endometrium and caruncles the increase was significant in the 5-day treatment group (p < 0.05). We conclude that the expression of type I NOS and type 111 NOS in the uterus are differentially regulated by estrogen. This differential regulation suggests that the NO produced within the uterus serves more than one physiological role. In myometrium it mar be a uterorelaxant and regulate glucose utilization, and in endometrium and myometrium it mar regulate blood flow.
650 $aEndocrinologia
650 $aEstrógeno
650 $aOvino
650 $aPrenhez
650 $aReprodução Animal
650 $aÚtero
700 1 $aMASSMANN, G. A.
700 1 $aMIRABILE, C. P.
700 1 $aFIGUEROA, J. P.
773 $tBiology of Reproduction$gv. 60, n. 5, p. 1198-1203, 1999.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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| Registros recuperados : 4 | |
| 2. |  | GÓMEZ, I.; SÁNCHEZ, J.; LIMA, C.; MARTINS, E.; ROSALES-JUÁREZ, A.; AGUILAR-MEDEL, S.; ABAD, A.; DONG, H.; PONTES, R. G. M. S. de; PEÑA, G.; ZHANG, J.; NELSON, M.; WU, G.; BRAVO, A.; SOBERÓN, M. Enhancement of Bacillus thuringiensis Cry1Ab and Cry1Fa toxicity to Spodoptera frugiperda by domain III mutations indicates there are two limiting steps in toxicity as defined by receptor binding and protein stability Applied and Environmental Microbiology, v. 84, n. 20, article e01393-18, 2018. Na publicação: Rose Monnerat.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 3. | | KUHN, J.; ADKINS, S.; AGWANDA, B. R.; KUBRUSLI, R. A.; ALKHOVSKY, S. V.; AMARASINGHE, G. K.; TATJANA, A.-Z.; AYLLÓN, M. A.; BAHL, J.; BALKEMA BUSCHMANN, A.; BALLINGER, M. J.; BASLER, C. F.; BAVARI, S.; BEER, M.; BEJERMAN, N.; BENNETT, A. J.; DBENTE, D. A.; BERGERON, É.; BIRD, B. H.; BLAIR, C. D.; BLASDELL, K. R.; BLYSTAD, D. R.; BOJKO, J.; BORTH, W. B.; BRADFUTE, S.; BREYTA, R.; BRIESE, T.; BROWN, P. A.; BROWN, J. K.; BUCHHOLZ, U. J.; BUCHMEIER, M. J.; ABUKREYEV, A.; BURT, F.; BÜTTNER, C.; CALISHER, C. H.; CAO, M.; CASAS, I.; CHANDRAN, K.; CHARREL, R. N.; CHENG, Q.; CHIAKI, Y.; CHIAPELLO, M.; CHOI, I. R.; CIUFO, M.; CLEGG, J. C. S.; CROZIER, I.; BÓ, E. D.; DE LA TORRE, J. C.; LAMBALLERIE, X. de; SWART, R. L. de; DEBAT, H.; DHEILLY, N. M.; DI CICCO, E.; DI PAOLA, N.; DI SERIO, F.; DIETZGEN, R. G.; DIGIARO, M.; DOLNIK, O.; DREBOT, M. A.; DREXLER, J. F.; DUNDON, W. G.; DUPREX, W. P.; DÜRRWALD, R.; DYE, J. M.; EASTON, A. J.; EBIHARA, H.; ELBEAINO, T.; ERGÜNAY, K.; FERGUSON, H. W.; FOOKS, A. R.; FORGIA, M.; FORMENTY, P. B. H.; FRÁNOVÁ, J.; ASTUA, J. de F.; FU, J.; FÜRL, S.; ZACHERT, S. G.; GĀO, G. F.; GARCÍA, M. L.; SASTRE, A. G.; GARRISON, A. R.; GASKIN, T.; GONZALE, J. P. J.; GRIFTHS, A.; GOLDBERG, T. L.; GROSCHUP, M. H.; GÜNTHER, S.; HALL, R. A.; HAMMOND, J.; HAN, O.; HEPOJOKI, J.; HEWSON, R.; HONG, J.; HONG, N.; HORIE, M.; HU, J. S.; HU, T.; HUGHES, H. R.; HÜTTNER, F.; HYNDMAN, T. H.; ILYAS, M.; JALKANEN, R.; JIĀNG, D.; JONSON, G. J.; JUNGLEN, S.; KADONO, F.; KAUKINEN, K. H.; KAWATE, M.; KLEMPA, B.; KLINGSTRÖM, J.; KOBINGER, G.; KOLONIUK, I.; KONDŌ, H.; KOONIN, V.; KRUPOVIC, M.; KUBOTA, K.; KURATH, G.; LAENEN, L.; LAMBERT, A. J.; LANGEVIN, S. L.; LEE, B.; LEFKOWITZ, E. J.; LI, L.; LEROY, E. M.; LI, S.; LÍ, J.; LIU, H.; LUKASHEVICH, I. S.; MAES, P.; SOUZA, W. M. de; MARKLEWITZ, M.; MARSHALL, S. H.; MARZANO, S. L.; MASSART, S.; MCCAULEY, J. W.; MELZER, M.; MILLER, K. M.; MING, T. J.; MIRAZIMI, A.; MORDECAI, G. J.; MÜHLBACH, H. P.; MÜHLBERGER, E.; NAIDU, R.; NATSUAKI, T.; NAVARRO, J. A.; NETESOV, S. Y V.; NEUMANN, G.; NOWOTNY, N.; NUNES, M. R. T.; VELARDE, A. O.; PALACIOS, G.; PALLÁS, V.; PÁLYI, B.; PAPA, A.; PARASKEVOPOULOU, S.; PARK, A. C.; PARRISH, C. R.; PATTERSON, D. A.; CORRÊA, A. P.; PAWESKA, J. T.; PAYNE, S.; PERACCHIO, C.; PÉREZ, D. R.; POSTLER, T. S.; QI, L.; RADOSHITZKY, S. R.; RESENDE, R. O.; REYES, C. A.; RIMA, B. K.; LUNA, G. R.; ROMANOWSKI, V.; ROTA, P.; RUBBENSTROTH, D.; RUBINO, L.; RUNSTADLER, J. A.; SABANADZOVIC, S.; SALL, A. A.; SALVATO, M. S.; SANG, R.; SASAYA, T.; SCHULZE, A. D.; SCHWEMMLE, M.; SHI, M.; SHÍ, X.; SHIMOMOTO, Y.; SHIRAKO, Y.; SIDDELL, S. G.; SIMMONDS, P.; SIRONI, M.; SMAGGHE, G.; SMITHER, S.; SONG, J. W.; SPANN, K.; SPENGLER, J. R.; STENGLEIN, M. D.; STONE, D. M.; SUGANO, J.; TABATA, A.; TAKADA, A.; TAKEUCHI, S.; TCHOUASSI, D. P.; TEFER, A.; TESH, R. B.; THORNBURG, N. J.; TOMITAKA, Y.; TOMONAGA, K.; TORDO, N.; TORTO, B.; TOWNER, J. S.; TSUDA, S.; TU, C.; TURINA, M.; TZANETAKIS, I. E.; UCHIDA, J.; USUGI, T.; VAIRA, A. M.; VALLINO, M.; VAN DEN HOOGEN, B.; VARSANI, A.; VASILAKIS, N.; VERBEEK, M.; BARGEN, S. V.; WADA, J.; WAHL, V.; WALKER, P. J.; WANG, L. F.; WANG, G.; WANG, Y.; WANG, Y.; WAQAS, M.; WÈI, T.; WEN, S.; WHITFELD, A. E.; WILLIAMS, J. V.; WOLF, Y. I.; WU, J.; XU, L.; YANAGISAWA, H.; YANG, C.; YANG, Z.; ZERBINI, F. M.; ZHAI, L.; ZHANG, Y. Z.; ZHANG, O.; ZHANG, J.; ZHANG, Z.; ZHOU, X. 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirale. Archives of Virology, August, 2021.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
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| 4. | | PASTORELLO, G.; TROTTA, C.; CANFORA, E.; CHU, H.; CHRISTIANSON, D.; CHEAH, Y.; POINDEXTER, C.; CHEN, J.; ELBASHANDY, A.; HUMPHREY, M.; ISAAC, P.; POLIDORI, D.; RIBECA, A.; VAN INGEN, C.; ZHANG, L.; AMIRO, B.; AMMANN, C.; ARAIN, M. A.; ARDÖ, J.; ARKEBAUER, T.; ARNDT, S. K.; ARRIGA, N.; AUBINET, M.; AURELA, M.; BALDOCCHI, D.; BARR, A.; BEAMESDERFER, E.; BELELLI, L. M.; BERGERON, O.; BERINGER, J.; BERNHOFER, C.; BERVEILLER, D.; BILLESBACH, D.; BLACK, T. A.; BLANKEN, P. D.; BOHRER, G.; BOIKE, J.; BOLSTAD, P. V.; BONAL, D.; BONNEFOND, J.; BOWLING, D. R.; ROSVEL, B.; BRODEUR, J.; BRÜMMER, C.; BUCHMANN, N.; BURBAN, B.; BURNS, S. P.; BUYSSE, P.; CALE, P.; CAVAGNA, M.; CELLIER, P.; CHEN, S.; CHINI, I.; CHRISTENSEN, T. R.; CLEVERLY, J.; COLLALTI, A.; CONSALVO, C.; COOK, B. D.; COOK, D.; COURSOLLE, C.; CREMONESE, E.; CURTIS, P. S.; D'ANDREA, E.; ROCHA, H. da; DAI, X.; DAVIS, K. J.; DE CINTI, B.; DE GRANDCOURT, A.; DE LIGNE, A.; OLIVEIRA JUNIOR, R. C. de; DELPIERRE, N.; DESAI, A. R.; DI BELLA, C. M.; DI TOMMASI, P.; DOLMAN, H.; DOMINGO, F.; DONG, G.; DORE, S.; DUCE, P.; DUFRÊNE, E.; DUNN, A.; DUSEK, J.; EAMUS, D.; EICHELMANN, U.; ELKHIDIR, H. A. M.; EUGSTER, W.; EWENZ, C. M.; EWERS, B.; FAMULARI, D.; FARES, S.; FEIGENWINTER, I.; FEITZ, A.; FENSHOLT, R.; FILIPPA, G.; FISCHER, M.; FRANK, J.; GALVAGNO, M.; GHARUN, M.; GIANELLE, D.; GIELEN, B.; GIOLI, B.; GITELSON, A.; GODED, I. B.; GOECKEDE, M.; GOLDSTEIN, A. H.; GOUGH, C. M.; GOULDEN, M. L.; GRAF, A.; GRIEBEL, A.; GRUENING, C.; GRÜNWALD, T.; HAMMERLE, A.; HAN, S.; HAN, X.; HANSEN, B. U.; HANSON, C.; HATAKKA, J.; HE, Y.; HEHN, M.; HEINESCH, B.; HINKO-NAJERA, N.; HÖRTNAGL, L.; HUTLEY, L.; IBROM, A.; IKAWA, H.; JACKOWICZ-KORCZYNSKI, M.; JANOUS, D.; JANS, W.; JASSAL, R.; JIANG, S.; KATO, T.; KHOMIK, M.; KLATT, J.; KNOHL, A.; KNOX, S.; KOBAYASHI, H.; KOERBER, G.; KOLLE, O.; KOSUGI, Y.; KOTANI, A.; KOWALSKI, A.; KRUIJT, B.; KURBATOVA, J.; KUTSCH, W. L.; KWON, H.; LAUNIAINEN, S.; LAURILA, T.; LAW, B.; LEUNING, R.; LI, Y.; LIDDELL, M.; LIMOUSIN, J.; LION, M.; LISKA, A.; LOHILA, A.; LÓPEZ-BALLESTEROS, A.; LÓPEZ-BLANCO, E.; LOUBET, B.; LOUSTAU, D.; LUCAS-MOFFAT, A.; LÜERS, J.; MA, S.; MACFARLANE, C.; MAGLIULO, V.; MAIER, R.; MAMMARELLA, I.; MANCA, G.; MARCOLLA, B.; MARGOLIS, H.; MARRAS, S.; MASSMAN, W.; MASTEPANOV, M.; MATAMALA, R.; MATTHES, J. H.; MAZZENGA, F.; MCCAUGHEY, H.; MCHUGH, I.; MCMILLAN, A. M. S.; MERBOLD, L.; MEYER, W.; MEYERS, T.; MILLER, S. D.; MINERBI, S.; MODEROW, U.; MONSON, R. K.; MONTAGNANI, L.; MOORE, C. E.; MOORS, E.; MOREAUX, V.; MOUREAUX, C.; MUNGER, J. W.; NAKAI, T.; NEIRYNCK, J.; NESIC, Z.; NICOLINI, G.; NOORMETS, A.; NORTHWOOD, M.; NOSETTO, M.; NOUVELLON, Y.; NOVICK, K.; WALTER, O.; OLESEN, J. E.; OURCIVAL, J.; PAPUGA, S. A.; PARMENTIER, F.; PAUL-LIMOGES, E.; PAVELKA, M.; PEICHL, M.; PENDALL, E.; PHILLIPS, R. P.; PILEGAARD, K.; PIRK, N.; POSSE, G.; POWELL, T.; PRASSE, H.; PROBER, S. M.; RAMBAL, S.; RANNIK, U.; RAZ-YASEEF, N.; REED, D.; RESCO DE DIOS, V.; RESTREPO-COUPE, N.; REVERTER, B. R.; ROLAND, M.; SABBATINI, S.; SACHS, T.; SALESKA, S. R.; SÁNCHEZ-CAÑETE, E. P.; SANCHEZ-MEJIA, Z. M.; SCHMID, H. P.; SCHMIDT, M.; SCHNEIDER, K.; SCHRADER, F.; SCHRODER, I.; SCOTT, R. L.; SEDLÁK, P.; SERRANO-ORTÍZ, P.; SHAO, C.; SHI, P.; SHIRONYA, I.; SIEBICKE, L.; SIGUT, L.; SILBERSTEIN, R.; SIRCA, C.; SPANO, D.; STEINBRECHER, R.; STEVENS, R. M.; STURTEVANT, C.; SUYKER, A.; TAGESSON, T.; TAKANASHI, S.; TANG, Y.; TAPPER, N.; THOM, J.; TIEDEMANN, F.; TOMASSUCCI, M.; TUOVINEN, J.; URBANSKI, S.; VALENTINI, R.; VAN DER MOLEN, M.; VAN GORSEL, E.; VAN HUISSTEDEN, K.; VARLAGIN, A.; VERFAILLIE, J.; VESALA, T.; VINCKE, C.; VITALE, D.; VYGODSKAYA, N.; WALKER, J. P.; WALTER-SHEA, E.; WANG, H.; WEBER, R.; WESTERMANN, S.; WILLE, C.; WOFSY, S.; WOHLFAHRT, G.; WOLF, S.; WOODGATE, W.; YUELIN, L.; ZAMPEDRI, R.; ZHANG, J.; ZHOU, G.; ZONA, D.; AGARWAL, D.; BIRAUD, S.; TORN, M.; PAPALE, D. The FLUXNET2015 dataset and the ONEFlux processing pipeline for eddy covariance data. Scientific Data, v. 7, Article number 225, 2020. 27 p.| Biblioteca(s): Embrapa Amazônia Oriental. |
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